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Suppositories have long been an important means of delivering certain medicines while increasing efficacy, localizing its effects, and avoiding side effects associated with other routes of administration. However, now weed suppositories with THC, CBD and other botanicals can provide natural relief for women of all ages.

Cannabis Suppositories:  Feel Healthy, Not High | Hello Again


Cannabis suppositories are a GYNOMITE method for administering cannabis that is gaining popularity among those who use cannabis for wellness. Suppositories are small (but mighty!), bullet-shaped objects that are inserted into the rectum or vagina. Suppsositories deliver a range of benefits without the psychoactive effects associated with smoking or ingesting cannabis.

How does this work?  It’s all about the body’s endocannabinoid system.  We all have one;  in fact, all animals, including vertebrates (mammals, birds, reptiles, and fish) as well as invertebrates (sea urchins, leeches and mussels) have been found to have endocannabinoid systems.  Within this system, the body makes cannabinoids in response to systemic imbalance. Sleep system wonky?  Your body makes cannabinoids.  Temperature control on the fritz?  Your body makes cannabinoids.  Mental clarity elusive?  Your body makes cannabinoids.  When those free-roaming cannabinoids reach cannabinoid receptors embedded all over the body, the biological goal is to restore balance.  

Putting Cannabinoids where it Counts

A cannabis suppository places the cannabinoids from the cannabis plant  (like THC and CBD!) in the female reproductive tract. The female reproductive tract houses the body’s second most dense collection of cannabinoid receptors.  That’s right, with the placement of the cannabis directly in that dense collection of cannabinoid receptors, the endocannabinoid system is quickly engaged to restore emotional, physical and cognitive balance.  

Additionally, when cannabis is administered in suppository form, it is absorbed through the mucous membranes of the rectum or vagina, allowing for rapid absorption and cues from tissue to tissue to relax and calm. CBD is an anti-inflammatory and muscle relaxer.  THC is a vasodilator, encouraging blood flow.  This brings efficient and effective relief for conditions like menstrual cramps, pelvic pain, and gastrointestinal issues, as it can deliver targeted relief to the affected area.

Because suppositories do not pass through the liver, the psychoactive effects of cannabis are greatly reduced. This allows users to experience therapeutic benefits without feeling high or intoxicated. This can be especially helpful for those who need to use cannabis during the day but need to remain alert and focused.  

It’s important to note that any cannabis product, especially cannabis suppositories, need to be purchased through a licensed, regulated entity.  This ensures product purity through lab-testing and strict regulations.  To learn more about the testing requirements for legal cannabis products read here.

Cannabis SuppositorY: The Magic Bullet!

Cannabis suppositories can avoid psychoactivity because they are absorbed through the rectum or vagina and directly into the bloodstream, bypassing the liver. When cannabis is ingested orally, it goes through the digestive system and liver before entering the bloodstream. In the bloodstream, it is converted into a more potent form of THC called 11-hydroxy-THC. This process can result in stronger and longer-lasting psychoactive effects.  This explains the wonky unexpected high that often accompanies edibles.  

When cannabis is administered in suppository form, it is absorbed through the mucous membranes of the rectum or vagina, and it enters the bloodstream without going through the liver. As a result, the THC and other cannabinoids in the cannabis are metabolized differently and do not undergo the same conversion process into 11-hydroxy-THC, which is more potent and psychoactive.

Furthermore, the dose of THC and other cannabinoids in a suppository can be carefully controlled and adjusted to minimize psychoactive effects while maximizing the therapeutic benefits. This means that users can receive the benefits of cannabis without experiencing the psychoactive effects that can interfere with daily activities.


The suppository also allows opportunity to address vaginal dryness, which is a very common problem for women of all ages.  Hello Again formulated a base specially to soothe and bring moisture to the vaginal walls.  The cocoa butter, vitamin E and avocado oil base soothes and and freshens as it melts and is absorbed.  

When Carrie and Patty learned about the endocannabinoid system, and that the cannabinoids in the cannabis have the same effect as our internally produced cannabinoids, they had a real A-Ha! Moment.  They were in the midst of menopause and it seemed none of their systems were in balance.  The creation of Hello Again cannabis suppositories was a result of Carrie and Patty wanting to use cannabis to bring balance to their menopause-affected body’s systems, but not wanting the associated psychoactive high.  Adult women of all ages are now using their line of products for relief and wellness.  That’s GYNOMITE!

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